Ahelixbiotech

In this review, we systematically categorize diverse organoid engineering strategies including cellular programming, material engineering, and platform- or system-level innovations according to their impact on reproducibility and scalability, and highlight representative applications and emerging directions. By reframing organoid generation as a manufacturing process, these technological advances pave the way toward standardized and high-fidelity organoid production for both fundamental research and translational applications. Original link: https://www.nature.com/articles/s44385-025-00054-6